Palliative intravenous cisplatin treatment for concurrent peritoneal and pleural mesothelioma in a dog.
J Vet Med Sci. 2007 Feb;69(2):201-4
Authors: Seo KW, Choi US, Jung YC, Hong SJ, Byeun YE, Kang MS, Pachrin B, Kim WH, Hwang CY, Kim DY, Youn HY, Lee CW
A 10-year-old Maltese dog was presented with abdominal distention and dyspnea. Cytological examination of pleural and peritoneal effusion was suggestive of malignant effusion of glandular origin. Numerous, multifocal, tan to white nodules were disseminated throughout the surface of the abdominal organs and peritoneum at biopsy. Histologically, the tumors were revealed to be an epithelial type of mesothelioma. Neoplastic cells co-expressed cytokeratin and vimentin. Intravenous administration of cisplatin was chosen as the treatment. During treatment, the dog's overall body condition improved and the clinical signs were relieved without significant side effects. The survival time from diagnosis to sudden death by unknown cause was 153 days.
PMID: 17339766 [PubMed - in process]
Click Here to read the entire article...
